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Actonel is an osteoporosis treatment medication available by prescription and used to stop bone loss and bone frailty when women are going through menopause or are post-menopausal. Risedronate is a bisphosphonate drug the slows bone loss and re-establishes strength and rigidity in bones, so they are less likely to crack or break over time. Actonel: Side effects As with most drugs, it's possible to have side effects with Actonel. These can include some mild side effects but also some serious ones. To learn more about Actonel's side effects, talk with your doctor or pharmacist. They may also provide information about managing certain side effects of this drug. Actonel (risedronate) is a brand-name prescription drug that's used for certain bone conditions, including osteoporosis. Learn about side effects and more. Availability: Brand Actonel (Proctor & Gamble; Aventis), generic Actonel (primarily Cipla), Actonel 35 mg once-a-week, Actonel 150 mg one-a-month pills. How Risedronate Works Risedronate is a medication that belongs to the family of medicines known as Bisphosphonates. Actonel and its generic counter- part are used to treat and prevent osteoporosis. Get the best price on Actonel at pharmacies near you with SingleCare. Save up to 80% with our Actonel coupons – with or without insurance! When Actonel is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Risedronate Sodium or Actonel Savings, Coupons and Information. | RISEDRONATE (ris ED roe nate) prevents and treats osteoporosis. It may also be used to treat Paget's disease of the bone. Over-the-Counter (OTC) Medications The United States has more than 80 classes of over-the-counter (OTC) medications. OTC drugs are considered safe and effective for public use without requiring consultation from a healthcare professional. 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