Xifaxan is a rifamycin which works by killing bacteria that causes infection. The most common form of Xifaxan is a 550mg tablet. It is also available as a 200mg tablet. There are currently no generic alternatives for Xifaxan. It is covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Compare generic Xifaxan (rifaximin) prices from accredited international online pharmacies, U.S. mail-order pharmacies, and discount coupon programs. The lowest available price for generic Xifaxan (rifaximin) 550 mg is $0.61 per tablet for 200 tablets at PharmacyChecker-accredited online pharmacies. Compare Xifaxan prices at 60,000+ US pharmacies. Get a free Rx.com coupon and save up to 90% on your prescription. Get the best price on Xifaxan at pharmacies near you with SingleCare. Save up to 80% with our Xifaxan coupons – with or without insurance! Xifaxan Prices, Coupons, Copay Cards & Patient Assistance Prices Coupons Patient assistance Xifaxan (rifaximin) is a member of the miscellaneous antibiotics drug class and is commonly used for Diarrhea, Hepatic Encephalopathy, Irritable Bowel Syndrome, and others. The cost for Xifaxan 550 mg oral tablet is around $4,339 for a supply of 60 tablets, depending on the pharmacy you visit. Quoted … Get the facts on cost and Xifaxan, how the generic compares with the brand name, what financial assistance may be available, and more. Xifaxan Prices (rifaximin) Compare Xifaxan prices from accredited international online pharmacies, U.S. mail-order pharmacies, and discount coupon programs. The lowest available price for Xifaxan 550 mg is $8.78 per tablet for 180 tablets at PharmacyChecker-accredited online pharmacies. The lowest listed cash price we found for Xifaxan 550 mg (60 ct) is $3839.09 at BetterBuy Rx, based on 1 pharmacy listing checked October 19, 2026. Confirm the matching formulation, pack, eligibility and final price with the pharmacy. Transfer your prescription for XIFAXAN 550 MG TAB on Amazon Pharmacy. FREE SHIPPING for Prime members. Compare Xifaxan prices at CVS, Walgreens, Walmart & more. Free RxDiff discount card — save up to 80% with no insurance needed. Xifaxan (rifaximin) Savings – ordering the generic from abroad With Xifaxan projected to enjoy patent protection until 2029, cost relief through generic competition isn't exactly around the corner domestically. By choosing generic Rifaximin, patients can save over 90% compared to the retail price of Xifaxan. This makes it a highly cost-effective alternative for those requiring long-term treatment or repeated courses of the medication. Frequently Asked Questions about Xifaxan 1. Is Xifaxan covered by insurance? Yes, Xifaxan is covered by most health insurance plans, including Medicare and Medicaid … The total cost of treatment without insurance could range from $421 (three days) to thousands of dollars (for longer treatments). Generic Xifaxan (rifaximin) is not yet available in the United States. A manufacturer's savings card or patient assistance program may help lower the cost of Xifaxan for eligible patients. Buy Xifaxan 550mg Tablets 56 – Rifaximin Online at Chemist Warehouse Always read the label and follow the directions for use. U.S. Retail Prices for Xifaxan (Rifaximin) Retail pharmacy prices remain high for Xifaxan (Rifaximin). Based on recent April 2025 data, the average cost for a 30-day supply at major local pharmacies includes: Jewel-Osco: $1,582.00 Walgreens: $1,782.00 Walmart: $1,803.00 Target: $1,729.00 Meijer: $1,668.00 Ready to purchase your medication for up to 80% off? Visit Planet Drugs Direct. The price reduction is a direct consequence of increased competition and the ability of payers to negotiate lower prices with multiple generic manufacturers. What are the Projected Market Dynamics and Sales Forecasts for XIFAXAN? Xifaxan is a prescription drug used to treat some types of diarrhea and certain other conditions. Learn about the drug's cost, how to find savings, and more. Learn about Xifaxan (rifaximin) usage and dosing. Read the latest news and reviews about the drug as well as potential side effects and popular alternatives. Xifaxan in 2026 too expensive? Find manufacturer coupons, pharmacy discounts, generic options, and the best prices at pharmacies near you on Medfinder. Generic medications may be manufactured by different companies. This means some generics vary in size, color, and shape. But the active ingredients are always the same. Amazon Pharmacy uses different manufacturers to ensure medication supply and offer low prices for our customers. Xifaxan costs about $461 for six tablets. Learn how the Xifaxan coupon, Xifaxan savings card, and other tools can help you save. Xifaxan is prescribed to treat certain types of diarrhea and to lower the risk of a brain condition in adults with severe liver disease. It's a brand-name drug, available as the generic medication rifaximin. It comes as an oral tablet. The cost with or without insurance can depend on several factors. It might be lowered by using a coupon. Why is Xifaxan so expensive? Xifaxan (rifaximin) is a brand-name drug manufactured by Salix Pharmaceuticals. It is an effective treatment option for irritable bowel syndrome with diarrhea (IBS-D), traveler's diarrhea, and hepatic encephalopathy. Learn more about Xifaxan pricing, uses, and interactions. WellRx helps you find the cheapest pharmacy deals and drug savings. Xifaxan (generic name rifaximin) is an antibiotic primarily used for treating irritable bowel syndrome (IBS), travelers' diarrhea, and hepatic encephalopathy. It's proven to be a preferred option for many, thanks in large part to its localized mechanism of action in the gut and fewer systemic side effects compared to other antibiotics. However, Xifaxan costs can be prohibitive for some … Compare the cost of prescription and generic Rifamycins medications. See information about popular Rifamycins, including the conditions they treat and alternatives available with or without insurance. Find Rifaximin generic drug prices and manufacturer details. Prices may vary by chemist. Click your brand name for cost information. Save on Rifaximin in 2026: compare pharmacy prices, find coupons, and discover discount programs. Medfinder helps you find the lowest price near you. Buy Xifaxan online and check Xifaxan generic, price, and cost for digestive infection and gut health treatment. Currently the lowest price for Xifaxan is $2803.76 on SaveHealth. Save money using our free Xifaxan coupons. Compare prices at pharmacies near you for different prescriptions. Check the cost and show the pharmacist our Xifaxan savings card to get your discount. Generic Xifaxan Availability Last updated on Sep 10, 2026. Is a generic available? Prices Patent protection Xifaxan is a brand name of rifaximin, approved by the FDA in the following formulation: Xifaxan is a brand-name drug, which means there is no widely available generic version in the United States at this time. Brand-name status often keeps prices high due to research, patent protection, and market exclusivity. Rifaximin Coupons & Savings Card – Discount Prices from $772.70 Generic for: Xifaxan Rifaximin, marketed under the name Xifaxan, is an antibiotic used primarily to treat diarrhea caused by E. coli, often referred to as "traveler's diarrhea," in individuals aged 12 and older. Xifaxan cost runs $2,350-$3,950 for 60 tablets at U.S. retail in 2026. See real prices by condition, what the new generic means, and how to pay less. Find information about patient assistance and insurance coverage for Xifaxan for adults with Overt Hepatic Encephalopathy. See Safety and Full Prescribing Information. Compare Rifaximin prices and find coupons that could save you up to 80% instantly at pharmacies near you such as CVS, Walgreens, Walmart, and many more. XIFAXAN® (rifaximin) 550 mg tablets are indicated for the reduction in risk of overt hepatic encephalopathy recurrence and for the treatment of IBS-D in adults. See Important Safety Information and full Prescribing Information on website. Treatment of irritable bowel syndrome with diarrhea (IBS-D). To lower the risk of hepatic encephalopathy, a brain condition caused by severe liver disease. Compare Xifaxan prices and find coupons that could save you up to 80% instantly at pharmacies near you such as CVS, Walgreens, Walmart, and many more. Generic Rifaximin is expected to become available around 2028-2029 when Xifaxan's patent exclusivity expires. Until then, Xifaxan remains the only Rifaximin product on the market, with cash prices of $1,600 to $2,200 per month. XIFAXAN ® (rifaximin) 550 mg tablets are indicated for the reduction in risk of overt hepatic encephalopathy (HE) recurrence in adults and for the treatment of irritable bowel syndrome with diarrhea (IBS-D) in adults.